Work Package 4: Antibiotic Stewardship Programme

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Work package 4 has the following objectives:

1. Develop evidence based antibiotic stewardship interventions to be implemented in the clinical study in work package 1.

2. Asses the effectiveness of antibiotic stewardship interventions based on patient case mix and most prevalent antimicrobial-resistant pathogens.

3. Test the integration of antibiotic stewardship recommendations with measures implemented in the infection prevention and control and microbiology and diagnostic stewardship availability.

4. Develop recommendations for clinical management strategies of severe infections caused by antimicrobial-resistant bacteria.

5. Provide clinical and epidemiological data to inform cost modelling to define the effectiveness of the stewardship modules by hospital setting and available resources, and define transferability including low-and-middle-income countries.

 

Leading Partner

University of Verona

 

Other Partners Involved

Andalusian Health Service, University of Florence

Publications
Publications
Relevant Publications
  • Carrara, E., Tebon, M., Morra, M., et al. (for the REVERSE Study Group). Towards tailored perioperative antibiotic prophylaxis: a multicentre pre-intervention analysis in the H2020 REVERSE project. Poster presented at: ESCMID Global 2025; 12-15 April 2025; Vienna, Austria. 

    Publication date: 12 April 2025

    Authors: E. Carrara, M. Tebon, M. Morra, A. Di Gioia, V. Mengardo, M. Genna, M. Da Meda, M.D. Pezzani, S. Zerva, A.R. Andritsos, I.M. Fieraru, D. Costin, I. Salcedo-Leal, C. Díaz-López, A. Sonpar, B. Rodriguez Bano, P. Retamar-Gentil, N. Zuabi Garcia, W .Zingg, E.

    Journal:

    Title: Towards tailored perioperative antibiotic prophylaxis: a multicentre pre-intervention analysis in the H2020 REVERSE project.

    Abstract:

    Link(s): -

    File(s): ESCMID Global 2025 - Towards tailored perioperative antibiotic prophylaxis: a multicentre pre-interv.pdf

  • Scardellato, R., Morra, M., Tebon, M., et al. (for the REVERSE Study Group). The role of early appropriate antibiotic treatment in febrile neuropenia: identifying targets for antimicrobial stewardship interventions. Poster presented at: ESCMID Global 2025; 12-15 April 2025; Vienna, Austria. 

    Publication date: 12 April 2025

    Authors: R. Scardellato, M. Morra, M. Tebon, A. Azzini, M. Negulescu, A. Anghel , P. Zisimopoulos, O. Ts o m p i k o u, A. Araújo, M. Pérez-Rodríguez, G. Nadali, C. Te c c h i o, A. Sonpar, J, Rodriguez Baño, P. Retamar, N, Garcia, W. Zingg 9, E. Ta c c o n e l l

    Journal:

    Title: The role of early appropriate antibiotic treatment in febrile neuropenia: identifying targets for antimicrobial stewardship interventions.

    Abstract:

    Link(s): -

    File(s): ESCMID Global 2025 - The role of early appropriate antibiotic treatment in febrile neutropaenia: ide.pdf

  • Araújo Ameijeiras, A, Vázquez Estévez, C, et al (for the REVERSE Study Group). Evaluación epidemiológica y terapéutica de pacientes con neutropenia febril antes de iniciar un PROA. Poster presented at: XXVII Congreso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica 2024; May 2024; Zaragoza, Spain. 

    Publication date: 30 May 2024

    Authors: Alejandro Araújo Ameijeiras, Claudia Vázquez Estévez, Irene Figueroa Parada , Paloma Picallo Lombardía, Antonio Pérez Landeiro, Lucía Martínez Lamas, Pilar Retamar-Gentil, Elena Carrara, Ma Teresa Pérez-Rodríguez

    Journal: ePoster at XXVII Congreso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica 2024

    Title: Evaluación epidemiológica y terapéutica de pacientes con neutropenia febril antes de iniciar un PROA.

    Abstract:

    Link(s): -

    File(s): SEIMC2024_NF_ePoster.pdf

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