Work Package 6: Economic Effectiveness
Work package 6 has the following objectives:
1. Estimate costs and health benefits associated with the interventions, including estimation of quality of life impact of infections.
2. Perform cost-effectiveness evaluations accounting for heterogeneity based on the clinical trial results.
3. Perform cost-effectiveness evaluations beyond the trial duration incorporating the impact on resistance and its health and cost consequences in the long term.
4. Conduct budget-impact analyses to provide estimates of affordability of tested interventions in different resource settings.
5. Identify potential barriers and facilitators of implementation in two selected low-and-middle-income countries.
Leading Partner
Other Partners Involved
Relevant Publications
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Pollard. J, Agnew, E. Pople, D. et al. (for the REVERSE Study Group). Cost and clinical impact of screening for CPE in hospitals: a cost-effectiveness model. Poster presented at; ESCMID Global 2025; 12-15 April 2025; Vienna, Austria.
Publication date: 12 April 2025
Authors: J. Pollard, E. Agnew, D. Pople, T. Whiteley, M. Leila, S. Uwais, K, Pouwels, N, Salant, J. Robotham, and the REVERSE Consortium
Journal:
Title: Cost and clinical impact of screening for CPE in hospitals: a cost-effectiveness model.
Abstract:
Link(s): -
File(s): REVERSE_ESCMID_2025_CPE_Screening_CE_Poster_v2-0.pdf
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Pollard, J., Agnew, E., Pearce-Smith, N., Pouwels, K.B., Salant, N., Robotham, J.V., and the REVERSE Consortium (2024). Umbrella review of economic evaluations of interventions for the prevention and management of healthcare-associated infections in adult hospital patients. Journal of Hospital Infection, 158, 47–60.
Publication date: 19 March 2025
Authors: J. Pollard, E. Agnew, N. Pearce-Smith, K.B. Pouwels, N. Salant, J.V. Robotham
Journal: The Journal of Hospital Infection
Title: Umbrella review of economic evaluations of interventions for the prevention and management of healthcare-associated infections in adult hospital patients
Abstract:
Link(s): https://www.journalofhospitalinfection.com/article/S0195-6701(25)00009-X/fullte…
File(s): Umbrella Review
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